pentobarbital will decrease the level or effect of clozapine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
pentobarbital will raise the stage or outcome of clopidogrel by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
Elderly or debilitated people may well respond to barbiturates with marked melancholy, pleasure, and confusion; in some patients, barbiturates repeatedly produce excitement instead of despair
pentobarbital will lower the extent or influence of eletriptan by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
To attenuate the potential of overdosage or the development of dependence, limit the prescribing and dispensing of sedative-hypnotic barbiturates, to the quantity necessary to the interval until finally the following appointment
pentobarbital will lessen the level or influence of triazolam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
fentanyl transdermal and pentobarbital equally boost sedation. Stay away from or Use Alternate Drug. Restrict use to sufferers for whom alternative treatment method choices are insufficient
pentobarbital increases effects of ifosfamide by influencing hepatic enzyme CYP2B6 metabolism. Use Warning/Check. Coadministration of ifosfamide with CYP2B6 inducers may possibly enhance metabolism of ifosfamide to its metabolite. Observe for increased results/toxicities if combined with CYP2B6 inducers.
pentobarbital will decrease the level or outcome of etravirine by impacting hepatic enzyme CYP2C9/ten metabolism. Use Caution/Watch.
pentobarbital will lessen the level or impact of ombitasvir/paritaprevir/ritonavir & dasabuvir (DSC) by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Potent CYP3A4 inducers may reduce partiaprevir and ritonavir concentrations, and for that reason lowered efficacy of Viekira Pak
pentobarbital will minimize the extent or influence of naloxegol by read more influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Utilization of naloxegol with robust CYP3A4 inducers isn't advised
pentobarbital will minimize the level or influence of tacrolimus by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
Check Intently (1)pentobarbital will lower the extent or impact of gefitinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will lessen the extent or result of almotriptan by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.